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Reflections on the system of evaluation of gene-edited livestock

Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 211-217 doi: 10.15302/J-FASE-2019303

Abstract: functions regarding economic traits, and new materials for livestock breeding have been obtained through geneediting (GE) and embryo manipulation with the purpose of improving quality and output and reducing theEvaluation is the most important component of the regulation of gene-edited livestock and is a crucialguarantee of public safety before the marketing of gene-edited animal products.Here, the system of evaluation of gene-edited livestock is discussed in terms of public safety and production

Keywords： evaluation gene editing livestock performance safety

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Gene-editing in plants no longer requires tissue culture

Yi ZHANG, Michael PALMGREN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 229-230 doi: 10.15302/J-FASE-2020330

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Application of Gene Editing Technology on Germplasm Resources

Han Hongbing, Xie Kabing, Cao Gang, Tian Jianhui, Wang Dong

Strategic Study of CAE 2018, Volume 20, Issue 6, Pages 82-86 doi: 10.15302/J-SSCAE-2018.06.013

Abstract:

Gene editing technology can precisely manipulate specific sites of the

Keywords： gene editing technology agricultural breeding agricultural germplasm innovation

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A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS

Frontiers of Agricultural Science and Engineering Pages 296-305 doi: 10.15302/J-FASE-2022479

Abstract:

● Summaries on sgRNAs design.

Keywords： CRISPR/Cas Aid-TG gene editing sgRNA design web server

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Advances in genetic engineering of domestic animals

Shaohua WANG,Kun ZHANG,Yunping DAI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1, Pages 1-10 doi: 10.15302/J-FASE-2016085

Abstract: Overall, genetic engineering has evolved through three stages in history: transgenesis, gene targeting, and gene editing.However, the low efficiency of gene targeting events in somatic cells prohibits its wide use in agriculturalRecently, rapid progress in tools and methods of genome engineering has been made, allowing genetic editing

Keywords： CRISPR TALEN ZFN gene editing livestock pig cattle

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Highlights of special issue “Genome Editing in Agriculture: Technology, Applications and Regulations”

Yaofeng ZHAO, Caixia GAO, Sen WU

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 121-122 doi: 10.15302/J-FASE-2019317

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Prospect of Medical Disruptive Technologies

Li Yongjie, Yang Juntao, Du Jian

Strategic Study of CAE 2018, Volume 20, Issue 6, Pages 64-68 doi: 10.15302/J-SSCAE-2018.06.010

Abstract: This paper mainly analyzes and evaluates five technical directions in tumor immunotherapy, gene editing

Keywords： medical technology disruptive technology tumor immunotherapy gene editing

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Base editing in pigs for precision breeding

Ruigao SONG, Yu WANG, Yanfang WANG, Jianguo ZHAO

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 161-170 doi: 10.15302/J-FASE-2019308

Abstract: Base editing has recently been developed as the latest gene-editing tool that can directly make changesThis review summarizes gene-editing developments and highlights recent genetic dissection related toSNPs in major economic traits which may have the potential to be modified using SNP-editing applicationsIn addition, limitations and future directions of base editing in pig breeding are discussed.

Keywords： base editing genetic improvement pigs single nucleotide polymorphisms

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Base editing technology

Yidi SUN, Erwei ZUO, Hui YANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 227-228 doi: 10.15302/J-FASE-2020321

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Search-and-replace editing of genetic information

Yao LIU, Xingxu HUANG, Xiaolong WANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 231-232 doi: 10.15302/J-FASE-2020322

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Embryo-mediated genome editing for accelerated genetic improvement of livestock

Zachariah MCLEAN, Björn OBACK, Götz LAIBLE

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 148-160 doi: 10.15302/J-FASE-2019305

Abstract: Genome editing technology with its ability to directly introduce beneficial sequence variants offersHowever, embryo-mediated precision editing by homology-directed repair (HDR) mechanisms is currentlybreeding scheme that overcomes the present efficiency limitations of HDR editing in bovine embryos.It integrates embryo-based genomic selection with precise multi-editing and uses embryonic cloning withelite edited blastomeres or embryonic pluripotent stem cells to resolve mosaicism, enable multiplex editing

Keywords： animal breeding cattle cloning CRISPR/Cas9 cytoplasmic injection embryo genome editing germline chimaeras

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Developments in genetic modification of cattle and implications for regulation, safety and traceability

Jan Pieter VAN DER BERG, Gijs A. KLETER, Evy BATTAGLIA, Martien A. M. GROENEN, Esther J. KOK

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 136-147 doi: 10.15302/J-FASE-2019306

Abstract:

Genetic modification techniques, in particular novel gene editing technologies, hold the yet unfulfilledGene editing technologies allow for the directed alteration of specific traits and thereby have the potential

Keywords： cattle food safety gene editing genetic modification GMO detection regulation

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A brief review of genome editing technology for generating animal models

Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 123-128 doi: 10.15302/J-FASE-2019309

Abstract:

The recent development of genome editing technologies has given researchers unprecedented power toThis mini-review briefly summarizes the development of major genome editing tools, focusing on the application

Keywords： animal model CRISPR genome editing TALEN ZFN

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The development and application of genome editing technology in ruminants: a review

Mengke YUAN, Yuanpeng GAO, Jing HAN, Teng WU, Jingcheng ZHANG, Yongke WEI, Yong ZHANG

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 171-180 doi: 10.15302/J-FASE-2019302

Abstract: development of transgenic breeding is proceeding slowly, because it suffers from low efficiency of geneHowever, new breeding methods combined with genome editing and somatic cell nuclear transfer or microinjectionRecent advances in precise genome editing technologies, especially clustered regularly interspaced shortand the state of the art and new insights into practical applications and social acceptance of genome editinggenome editing technology it is possible to help feed the world.

Keywords： bioreactors breeding engineered endonucleases genome editing ruminants